Mbappé opened the scoring for PSG with the fastest goal in the history of Ligue 1, eight seconds at Pierre-Mauroy Stadium, in Lille.
Messi doubled the lead in the 27th minute before Hakimi added another goal twelve minutes later to make it 3-0.
Neymar extended PSG’s lead to 4-0 just before the half-time whistle.
The Brazilian scored his second for the night after the resumption of play.
Jonathan Bamba a consolation goal for Lille in the 54th minute, two minutes after Neymar’s second goal.
However, red-hot Mbappé added two more goals in the 66th and 87th minute to make it 7-1.
The Parisians have now scored 17 goals in three matches in the Ligue 1 this season.